Pinch-hitter Ezequiel Carrera hit a tiebreaking solo home run in the eighth inning and Jose Bautista had a two-run shot in the sixth as the Blue Jays beat Tampa Bay 3-2.
The Red Sox still have a two-game lead on Toronto atop the A-L East after a 12-2 smashing of Baltimore.
Meanwhile, the Tigers are one game back of the Orioles for the second A-L wild card after Detroit doubled up Minnesota 4-2. Ian Kinsler and Miguel Cabrera both hit home runs for the Tigers.
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Carlos Hyde ran for 88 yards and two touchdowns as the San Francisco 49ers spoiled the Rams' first game since moving back to Los Angeles with a 28-0 victory.
In other NFL action, Ben Roethlisberger threw three touchdown passes to lead the Steelers to a 38-16 victory over the Redskins in Washington.
