Gregory Line will be closing between Arkwood and Centre Side Road for four months, beginning this week.
The Municipality of Chatham-Kent says the road will be closed for construction on Thursday, November 30, and won't reopen until March 29.
According to the municipality, all lanes will be closed 500m west of Arkwood Road. Local traffic will have access up to the work zone, while emergency vehicles will not have access through the work zone.
The work includes culvert replacement over the Louisville Tap Drain.